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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:25549
Term: nitrites
Definition: null
Chemical ID: MESH:D009573
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngmultiple interactionsEXP 6480464CTD[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites; [Lipopolysaccharides co-treated with IFNG] results in increased abundance of Nitrites; IFNG protein promotes the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitrites]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites]PMID:19071154 PMID:19457078 PMID:7532384
Ifngincreases abundanceISOIfng (Mus musculus)6480464CTDIFNG protein results in increased abundance of NitritesPMID:12845421 PMID:17727827 PMID:23942037
Ifngmultiple interactionsISOIFNG (Homo sapiens)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased chemical synthesis of Nitrites]; 2-amino-5,6-dihydro-6-methyl-4H-1,3-thiazine inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased chemical synthesis of Nitrites]; [IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites; [IL1B protein co-treated with IFNG protein] results in increased chemical synthesis of NitritesPMID:10532951 PMID:10903806
Ifngmultiple interactionsISOIfng (Mus musculus)6480464CTD2,2'-dihydroxychalcone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; 2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitrites]; [Curcumin co-treated with piperine] inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; [IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites; [Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitrites; [TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitrites; aristolochic acid I inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitrites]; carnosol inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; cobaltiprotoporphyrin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; Dimethyl Fumarate inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; eriodictyol inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; HMOX1 protein inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; HMOX1 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; HMOX1 protein promotes the reaction [carnosol inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; IL4 protein inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitrites]; Industrial Waste inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitrites]; isoliquiritigenin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; NFE2L2 protein inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; NFE2L2 protein promotes the reaction [2-tert-butylhydroquinone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; NFE2L2 protein promotes the reaction [carnosol inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; plumbagin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; pyrrolidine dithiocarbamic acid inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; salvin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitrites]; sulforaphane inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; tin protoporphyrin IX inhibits the reaction [[Curcumin co-treated with piperine] inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; tin protoporphyrin IX inhibits the reaction [carnosol inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; tin protoporphyrin IX inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; tin protoporphyrin IX inhibits the reaction [Dimethyl Fumarate inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; tin protoporphyrin IX inhibits the reaction [sulforaphane inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]; Tosyllysine Chloromethyl Ketone inhibits the reaction [IFNG protein results in increased abundance of Nitrites]PMID:10967106 PMID:12845421 PMID:19071154 PMID:21396992 PMID:23942037 PMID:24412304 PMID:9918806
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