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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2809
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxa3
Name: forkhead box A3
Acc ID: CHEBI:28088
Term: genistein
Definition: A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxa3multiple interactionsEXP 6480464CTD[Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of FOXA3 mRNA; [Genistein co-treated with Diethylhexyl Phthalate] results in decreased expression of FOXA3 mRNA; [Genistein co-treated with Diethylhexyl Phthalate] results in decreased expression of FOXA3 proteinPMID:25031359 PMID:36674726
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