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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gstp1
Name: glutathione S-transferase pi 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstp1affects expressionEXP 6480464CTDbisphenol A affects the expression of GSTP1 mRNAPMID:25181051 PMID:30903817
Gstp1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GSTP1 mRNA; bisphenol A results in decreased expression of GSTP1 proteinPMID:27208089 PMID:30816183 PMID:32145629 PMID:32528016
Gstp1increases expressionEXP 6480464CTDbisphenol A results in increased expression of GSTP1 mRNAPMID:35378123
Gstp1increases methylationEXP 6480464CTDbisphenol A results in increased methylation of GSTP1 genePMID:28505145
Gstp1decreases expressionISOGSTP1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of GSTP1 proteinPMID:34186270
Gstp1decreases methylationISOGSTP1 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of GSTP1 promoterPMID:31610501
Gstp1increases methylationISOGSTP1 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of GSTP1 genePMID:32466334
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