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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2268
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Capn2
Name: calpain 2
Acc ID: CHEBI:82818
Term: Z-Val-Phe-H
Definition: A dipeptide resulting from the formal condensation of the carboxy group of N-benzyloxycarbonyl-L-valine with the amino group of L-phenylalanine aldehyde. It is a potent cell-permeable inhibitor of calpain I and II, and is also a gamma-secretase inhibitor.
Chemical ID: MESH:C058076
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Capn2multiple interactionsEXP 6480464CTDcalpain inhibitor III inhibits the reaction [Isoflurane results in increased expression of CAPN2 protein]PMID:29289695
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