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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1624097
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c37
Name: cytochrome P450, family 2. subfamily c, polypeptide 37
Acc ID: CHEBI:7772
Term: omeprazole
Definition: A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.
Chemical ID: MESH:D009853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c37increases metabolic processingEXP 6480464CTDCYP2C37 protein results in increased metabolism of OmeprazolePMID:30503582
Cyp2c37multiple interactionsEXP 6480464CTD[CYP2C37 protein results in increased metabolism of Omeprazole] which results in increased chemical synthesis of 5-hydroxymethylomeprazolePMID:30503582
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