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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1623061
Species: Mus musculus
RGD Object: Gene
Symbol: Immp2l
Name: IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Immp2ldecreases expressionEXP 6480464CTDBenzo(a)pyrene metabolite results in decreased expression of IMMP2L mRNA; Benzo(a)pyrene results in decreased expression of IMMP2L mRNAPMID:19770486 PMID:20713471 PMID:21569818 PMID:21715664 PMID:22610609 PMID:32553695
Immp2ldecreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of IMMP2L intronPMID:27901495
Immp2laffects methylationISOIMMP2L (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of IMMP2L intronPMID:30157460
Immp2ldecreases expressionISOIMMP2L (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of IMMP2L mRNAPMID:20064835 PMID:20106945 PMID:21632981 PMID:22316170 PMID:26238291 PMID:32234424 PMID:35690182
Immp2ldecreases methylationISOIMMP2L (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of IMMP2L 5' UTR; Benzo(a)pyrene results in decreased methylation of IMMP2L promoterPMID:27901495
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