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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1607086
Species: Homo sapiens
RGD Object: Gene
Symbol: SKP2
Name: S-phase kinase associated protein 2
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SKP2decreases expressionEXP 6480464CTDGlyphosate results in decreased expression of SKP2 mRNAPMID:31295307
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