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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595950
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lpar6
Name: lysophosphatidic acid receptor 6
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lpar6affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of LPAR6 mRNAPMID:34747641
Lpar6decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of LPAR6 mRNAPMID:33387578
Lpar6increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of LPAR6 mRNAPMID:32109520
Lpar6affects expressionISOLpar6 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of LPAR6 mRNAPMID:21570461
Lpar6decreases expressionISOLPAR6 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of LPAR6 mRNAPMID:20106945 PMID:21632981
Lpar6increases expressionISOLpar6 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of LPAR6 mRNAPMID:20159946 PMID:21889950
Lpar6multiple interactionsISOLpar6 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of LPAR6 mRNAPMID:25975270
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