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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595093
Species: Rattus norvegicus
RGD Object: Gene
Symbol: L1td1
Name: LINE-1 type transposase domain containing 1
Acc ID: CHEBI:6651
Term: malathion
Definition: A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
Chemical ID: MESH:D008294
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
L1td1affects expressionEXP 6480464CTDMalathion affects the expression of L1TD1 mRNAPMID:36370973
L1td1increases methylationEXP 6480464CTDMalathion results in increased methylation of L1TD1 promoterPMID:36370973
L1td1multiple interactionsEXP 6480464CTD[Malathion results in increased methylation of L1TD1 promoter] which affects the expression of L1TD1 mRNAPMID:36370973
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