Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1593929
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Asap3
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Asap3decreases expressionISOASAP3 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of DDEFL1 mRNAPMID:23527032
Asap3increases expressionISOASAP3 (Homo sapiens)6480464CTDValproic Acid results in increased expression of ASAP3 mRNAPMID:26272509
Asap3increases methylationISOASAP3 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of ASAP3 genePMID:29154799
Asap3multiple interactionsISOASAP3 (Homo sapiens)6480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of DDEFL1 mRNA; [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ASAP3 mRNAPMID:17183730 PMID:27188386
Go Back to source page   Continue to Ontology report