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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589798
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gys1
Name: glycogen synthase 1
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gys1decreases phosphorylationISOGYS1 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased phosphorylation of GYS1 proteinPMID:30362509
Gys1decreases phosphorylationISOGys1 (Mus musculus)6480464CTDArsenic Trioxide results in decreased phosphorylation of GYS1 proteinPMID:30362509
Gys1multiple interactionsISOGYS1 (Homo sapiens)6480464CTD3-methyladenine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]; Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]; Rosiglitazone inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]PMID:30362509
Gys1multiple interactionsISOGys1 (Mus musculus)6480464CTDTaurine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of GYS1 protein]PMID:30362509
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