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GENE - TERM ANNOTATION REPORT

RGD ID: 1589772
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sh3rf3
Name: SH3 domain containing ring finger 3
Acc ID: GO:0061630
Term: ubiquitin protein ligase activity
Definition: Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S = X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
Definition Source(s): GOC:BioGRID, GOC:dph, GOC:mah, GOC:tb, PMID:22863777
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sh3rf3enablesISOSH3RF3 (Homo sapiens)1624291RGD PMID:20696164

PMID:20696164
Sh3rf3enablesIBAFB:FBgn0040294 or PANTHER:PTN000070286 or UniProtKB:Q7Z6J0 or UniProtKB:Q8TEC5 or UniProtKB:Q8TEJ31600115GO_CentralGO_REF:0000033

GO_REF:0000033
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