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GENE - TERM ANNOTATION REPORT

RGD ID: 1565585
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Snx12
Name: sorting nexin 12
Acc ID: GO:0030904
Term: retromer complex
Definition: A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.
Definition Source(s): GOC:bf, PMID:26220253, PMID:27385586, PMID:9700157
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Snx12part_ofIBAFB:FBgn0038065 or PANTHER:PTN002915357 or UniProtKB:O604931600115GO_CentralGO_REF:0000033

GO_REF:0000033
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