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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565342
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ly6e
Name: lymphocyte antigen 6 family member E
Acc ID: CHEBI:17026
Term: progesterone
Definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Chemical ID: MESH:D011374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ly6edecreases expressionISOLy6e (Mus musculus)6480464CTDProgesterone results in decreased expression of LY6E mRNAPMID:27264040 PMID:31566189
Ly6emultiple interactionsISOLy6e (Mus musculus)6480464CTDMifepristone inhibits the reaction [Progesterone results in decreased expression of LY6E mRNA]PMID:27264040 PMID:31566189
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