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GENE - TERM ANNOTATION REPORT

RGD ID: 1562034
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cep41
Name: centrosomal protein 41
Acc ID: GO:0036064
Term: ciliary basal body
Definition: A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodeling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
Definition Source(s): GOC:cilia, GOC:clt, PMID:21750193
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cep41located_inISOCEP41 (Homo sapiens)1624291RGD PMID:22246503

PMID:22246503
Cep41located_inISOCep41 (Mus musculus)1624291RGD PMID:22246503

PMID:22246503
Cep41located_inIEAUniProtKB:Q99NF3 or ensembl:ENSMUSP000000318101600115EnsemblGO_REF:0000107

GO_REF:0000107
Cep41located_inIEAUniProtKB:Q9BYV8 or ensembl:ENSP000002232081600115EnsemblGO_REF:0000107

GO_REF:0000107
Cep41is_active_inIBAMGI:1891414 or PANTHER:PTN002893044 or UniProtKB:Q581R0 or UniProtKB:Q9BYV81600115GO_CentralGO_REF:0000033

GO_REF:0000033
Cep41located_inISSUniProtKB:Q9BYV81600115UniProtGO_REF:0000024

GO_REF:0000024
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