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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ces2h
Name: carboxylesterase 2H
Acc ID: CHEBI:32234
Term: titanium dioxide
Definition: A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.
Chemical ID: MESH:C009495
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ces2hdecreases expressionISOCes2h (Mus musculus)6480464CTDtitanium dioxide results in decreased expression of CES2H mRNAPMID:31298478
Ces2hdecreases methylationISOCES2 (Homo sapiens)6480464CTDtitanium dioxide results in decreased methylation of CES2 3' UTRPMID:34973136
Ces2hmultiple interactionsISOCes2h (Mus musculus)6480464CTDResveratrol inhibits the reaction [titanium dioxide results in decreased expression of CES2H mRNA]PMID:31298478
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