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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560247
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cldn2
Name: claudin 2
Acc ID: CHEBI:6801
Term: metformin
Definition: A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Chemical ID: MESH:D008687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cldn2decreases expressionISOCLDN2 (Homo sapiens)6480464CTDMetformin results in decreased expression of CLDN2 proteinPMID:37121296
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