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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560165
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lrrc17
Name: leucine rich repeat containing 17
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lrrc17increases expressionEXP 6480464CTDEstradiol results in increased expression of LRRC17 mRNAPMID:32145629
Lrrc17multiple interactionsEXP 6480464CTD[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of LRRC17 mRNAPMID:32741896
Lrrc17decreases expressionISOLRRC17 (Homo sapiens)6480464CTDEstradiol results in decreased expression of LRRC17 mRNAPMID:23019147
Lrrc17increases expressionISOLrrc17 (Mus musculus)6480464CTDEstradiol results in increased expression of LRRC17 mRNAPMID:19484750
Lrrc17multiple interactionsISOLRRC17 (Homo sapiens)6480464CTD[Estradiol co-treated with Progesterone] results in decreased expression of LRRC17 mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of LRRC17 mRNAPMID:20660070 PMID:30165855
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