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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1559537
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Etv6
Name: ETS variant transcription factor 6
Acc ID: CHEBI:4911
Term: etoposide
Definition: A furonaphthodioxole that has formula C29H32O13.
Chemical ID: MESH:D005047
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Etv6increases mutagenesisISOETV6 (Homo sapiens)6480464CTDEtoposide results in increased mutagenesis of ETV6 genePMID:28624474
Etv6increases response to substanceISOETV6 (Homo sapiens)6480464CTDETV6 gene mutant form results in increased susceptibility to EtoposidePMID:15217836
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