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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14151254
Species: Sus scrofa
RGD Object: Gene
Symbol: HIF1A
Name: hypoxia inducible factor 1 subunit alpha
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HIF1Aincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of HIF1A mRNA; sodium arsenite results in increased expression of HIF1A proteinPMID:15089098
HIF1Amultiple interactionsEXP 6480464CTDbisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]; Go 6976 inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]PMID:15089098
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