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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359104
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppm1j
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1J
Acc ID: CHEBI:6980
Term: monocrotaline
Definition: A pyrrolizidine alkaloid that has formula C16H23NO6.
Chemical ID: MESH:D016686
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppm1jmultiple interactionsISOPPM1J (Homo sapiens)6480464CTD[CYP3A4 protein results in increased metabolism of Monocrotaline] which results in decreased expression of PPM1J mRNAPMID:33884520
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