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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359104
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppm1j
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1J
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppm1jdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PPM1J mRNAPMID:25181051
Ppm1jincreases expressionEXP 6480464CTDbisphenol A results in increased expression of PPM1J mRNAPMID:34947998
Ppm1jincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of PPM1J genePMID:28505145
Ppm1jdecreases methylationISOPpm1j (Mus musculus)6480464CTDbisphenol A results in decreased methylation of PPM1J promoterPMID:27312807
Ppm1jincreases methylationISOPpm1j (Mus musculus)6480464CTDbisphenol A results in increased methylation of PPM1J promoterPMID:27312807
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