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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353049
Species: Homo sapiens
RGD Object: Gene
Symbol: ELOVL5
Name: ELOVL fatty acid elongase 5
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ELOVL5affects methylationEXP 6480464CTDBenzo(a)pyrene affects the methylation of ELOVL5 5' UTRPMID:27901495
ELOVL5decreases expressionEXP 6480464CTDBenzo(a)pyrene results in decreased expression of ELOVL5 mRNAPMID:20064835
ELOVL5decreases methylationEXP 6480464CTDBenzo(a)pyrene results in decreased methylation of ELOVL5 promoterPMID:27901495
ELOVL5increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of ELOVL5 mRNAPMID:20498004
ELOVL5decreases expressionISOElovl5 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of ELOVL5 mRNAPMID:22228805
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