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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351093
Species: Homo sapiens
RGD Object: Gene
Symbol: ENG
Name: endoglin
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ENGaffects expressionISOEng (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of ENG mRNAPMID:34747641
ENGaffects expressionISOEng (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ENG mRNAPMID:21570461
ENGdecreases expressionISOEng (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of ENG mRNAPMID:26290441
ENGincreases expressionISOEng (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ENG mRNAPMID:24475139 PMID:32109520
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