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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347299
Species: Homo sapiens
RGD Object: Gene
Symbol: SMAD2
Name: SMAD family member 2
Acc ID: CHEBI:46661
Term: asbestos
Definition: Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements.
Chemical ID: MESH:D001194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SMAD2multiple interactionsEXP 6480464CTD[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in increased expression of SMAD2 mRNA; [Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in increased phosphorylation of SMAD2 proteinPMID:25358858
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