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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347299
Species: Homo sapiens
RGD Object: Gene
Symbol: SMAD2
Name: SMAD family member 2
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SMAD2increases phosphorylationEXP 6480464CTDTamoxifen results in increased phosphorylation of SMAD2 proteinPMID:17098229
SMAD2multiple interactionsEXP 6480464CTDTamoxifen promotes the reaction [Tretinoin results in increased phosphorylation of SMAD2 protein]PMID:17098229
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