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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346274
Species: Homo sapiens
RGD Object: Gene
Symbol: KIF11
Name: kinesin family member 11
Acc ID: CHEBI:31941
Term: oxaliplatin
Definition: A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer.
Chemical ID: MESH:C030110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KIF11decreases expressionISOKif11 (Rattus norvegicus)6480464CTDoxaliplatin results in decreased expression of KIF11 mRNAPMID:25729387
KIF11multiple interactionsISOKif11 (Rattus norvegicus)6480464CTD[oxaliplatin co-treated with Topotecan] results in decreased expression of KIF11 mRNAPMID:25729387
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