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GENE - TERM ANNOTATION REPORT

RGD ID: 1345063
Species: Homo sapiens
RGD Object: Gene
Symbol: FANCF
Name: FA complementation group F
Acc ID: GO:0043240
Term: Fanconi anaemia nuclear complex
Definition: A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
Definition Source(s): GOC:jl, PMID:12093742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FANCFpart_ofNAS 150520179ComplexPortal PMID:22343915

PMID:22343915
FANCFpart_ofIBAMGI:3689889 or PANTHER:PTN001426273 or UniProtKB:Q9NPI8150520179GO_Central GO_REF:0000033
FANCFpart_ofIEAInterPro:IPR035428150520179InterPro GO_REF:0000002
FANCFpart_ofIDA 150520179UniProt PMID:20347428

PMID:20347428
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