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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344024
Species: Homo sapiens
RGD Object: Gene
Symbol: FADS1
Name: fatty acid desaturase 1
Acc ID: CHEBI:17447
Term: geraniol
Definition: A monoterpenoid consisting of two prenyl units linked head-to-tail and functionalised with a hydroxy group at its tail end.
Chemical ID: MESH:C007836
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FADS1decreases activityEXP 6480464CTDgeraniol results in decreased activity of FADS1 proteinPMID:16462894
FADS1multiple interactionsEXP 6480464CTD[geraniol results in decreased activity of FADS1 protein] which results in decreased chemical synthesis of Arachidonic Acid; [geraniol results in decreased activity of FADS1 protein] which results in decreased metabolism of 8,11,14-Eicosatrienoic AcidPMID:16462894
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