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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311972
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l1
Name: NFE2 like bZIP transcription factor 1
Acc ID: CHEBI:1391
Term: 3,4-methylenedioxymethamphetamine
Definition: A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5.
Chemical ID: MESH:D018817
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l1decreases expressionISONfe2l1 (Mus musculus)6480464CTDN-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of NFE2L1 mRNAPMID:26251327
Nfe2l1decreases methylationISONfe2l1 (Mus musculus)6480464CTDN-Methyl-3,4-methylenedioxyamphetamine results in decreased methylation of NFE2L1 promoterPMID:26251327
Nfe2l1increases expressionISONfe2l1 (Mus musculus)6480464CTDN-Methyl-3,4-methylenedioxyamphetamine results in increased expression of NFE2L1 mRNAPMID:20188158
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