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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310883
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fpr1
Name: formyl peptide receptor 1
Acc ID: CHEBI:53490
Term: N-formyl-L-methionyl-L-leucyl-L-phenylalanine
Definition: A tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor.
Chemical ID: MESH:D009240
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fpr1multiple interactionsISOFPR1 (Homo sapiens)6480464CTDN-Formylmethionine Leucyl-Phenylalanine binds to and results in increased activity of FPR1 proteinPMID:17520823
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