Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1310780
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Hoxb3
Name:	homeo box B3

Acc ID:	CHEBI:44185
Term:	methotrexate
Definition:	A pteridine that has formula C20H22N8O5.
Chemical ID:	MESH:D008727

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Hoxb3	increases expression	ISO	HOXB3 (Homo sapiens)	6480464	CTD	Methotrexate results in increased expression of HOXB3 mRNA	PMID:24449571

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.