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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309603
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csta
Name: cystatin A
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cstadecreases expressionISOCSTA (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CSTA mRNAPMID:20106945 PMID:21632981
Cstaincreases expressionISOCSTA (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of CSTA mRNAPMID:19619570
Cstamultiple interactionsISOCSTA (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CSTA mRNAPMID:19619570
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