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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309089
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lsg1
Name: large 60S subunit nuclear export GTPase 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lsg1increases expressionEXP 6480464CTDbisphenol A results in increased expression of LSG1 mRNAPMID:34947998
Lsg1increases methylationEXP 6480464CTDbisphenol A results in increased methylation of LSG1 genePMID:28505145
Lsg1increases expressionISOLsg1 (Mus musculus)6480464CTDbisphenol A results in increased expression of LSG1 mRNAPMID:26063408
Lsg1multiple interactionsISOLSG1 (Homo sapiens)6480464CTD[Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of LSG1 proteinPMID:31629898
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