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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308845
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Reck
Name: reversion-inducing-cysteine-rich protein with kazal motifs
Acc ID: CHEBI:4775
Term: ellagic acid
Definition: An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates.
Chemical ID: MESH:D004610
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Reckincreases expressionISORECK (Homo sapiens)6480464CTDEllagic Acid results in increased expression of RECK mRNA; Ellagic Acid results in increased expression of RECK proteinPMID:21573219
Reckmultiple interactionsISORECK (Homo sapiens)6480464CTDzinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein]PMID:21573219
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