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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308669
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxp1
Name: forkhead box P1
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxp1decreases expressionISOFOXP1 (Homo sapiens)6480464CTDGlucose results in decreased expression of FOXP1 mRNA; Glucose results in decreased expression of FOXP1 proteinPMID:31494106
Foxp1multiple interactionsISOFOXP1 (Homo sapiens)6480464CTDAKT activator SC79 inhibits the reaction [FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of CYBB protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of NOX4 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]PMID:31494106
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