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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308205
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pard6b
Name: par-6 family cell polarity regulator beta
Acc ID: CHEBI:34342
Term: 3-methylcholanthrene
Definition: A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Chemical ID: MESH:D008748
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pard6bdecreases expressionISOPard6b (Mus musculus)6480464CTDMethylcholanthrene results in decreased expression of PARD6B mRNAPMID:20713471
Pard6bmultiple interactionsISOPard6b (Mus musculus)6480464CTD[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PARD6B mRNAPMID:23519560
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