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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307263
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Elovl3
Name: ELOVL fatty acid elongase 3
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Elovl3increases expressionISOElovl3 (Mus musculus)6480464CTDpirinixic acid results in increased expression of ELOVL3 mRNAPMID:16357043 PMID:17726147 PMID:18301758 PMID:18445702 PMID:23811191
Elovl3multiple interactionsISOELOVL3 (Homo sapiens)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ELOVL3 mRNAPMID:19710929
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