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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307241
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tmcc3
Name: transmembrane and coiled-coil domain family 3
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tmcc3increases expressionISOTmcc3 (Mus musculus)6480464CTDpirinixic acid results in increased expression of TMCC3 mRNAPMID:18301758 PMID:20813756 PMID:23811191
Tmcc3multiple interactionsISOTmcc3 (Mus musculus)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TMCC3 mRNA; [pirinixic acid co-treated with PPARA] results in increased expression of TMCC3 mRNAPMID:19710929 PMID:20813756
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