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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307207
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lama1
Name: laminin subunit alpha 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lama1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of LAMA1 mRNAPMID:25181051 PMID:30816183 PMID:34947998 PMID:38750585
Lama1increases methylationEXP 6480464CTDbisphenol A results in increased methylation of LAMA1 genePMID:28505145
Lama1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of LAMA1 mRNAPMID:36041667
Lama1decreases expressionISOLama1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of LAMA1 mRNAPMID:32156529
Lama1increases expressionISOLAMA1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of LAMA1 mRNA; bisphenol A results in increased expression of LAMA1 proteinPMID:27685785 PMID:29275510 PMID:37567409
Lama1increases expressionISOLama1 (Mus musculus)6480464CTDbisphenol A results in increased expression of LAMA1 mRNAPMID:33221593
Lama1multiple interactionsISOLAMA1 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of LAMA1 mRNAPMID:28628672
Lama1multiple interactionsISOLama1 (Mus musculus)6480464CTD[bisphenol A co-treated with LIF protein] results in decreased expression of LAMA1 mRNAPMID:30951980
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