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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306915
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Usp7
Name: ubiquitin specific peptidase 7
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Usp7affects expressionISOUSP7 (Homo sapiens)6480464CTDValproic Acid affects the expression of USP7 mRNAPMID:25979313
Usp7decreases expressionISOUSP7 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of USP7 mRNAPMID:28001369
Usp7increases methylationISOUSP7 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of USP7 genePMID:29154799
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