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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305864
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stk32c
Name: serine/threonine kinase 32C
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stk32caffects methylationISOSTK32C (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of STK32C intron; Benzo(a)pyrene affects the methylation of STK32C polyA tailPMID:30157460
Stk32cdecreases expressionISOSTK32C (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of STK32C proteinPMID:32717239
Stk32cincreases methylationISOSTK32C (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of STK32C promoterPMID:27901495
Stk32cincreases methylationISOStk32c (Mus musculus)6480464CTDBenzo(a)pyrene results in increased methylation of STK32C 5' UTR; Benzo(a)pyrene results in increased methylation of STK32C exon; Benzo(a)pyrene results in increased methylation of STK32C intronPMID:27901495
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