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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304740
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tspan9
Name: tetraspanin 9
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tspan9affects methylationISOTSPAN9 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of TSPAN9 3' UTR; Benzo(a)pyrene affects the methylation of TSPAN9 5' UTRPMID:27901495 PMID:30157460
Tspan9decreases expressionISOTspan9 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of TSPAN9 mRNAPMID:19770486
Tspan9decreases expressionISOTSPAN9 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of TSPAN9 mRNAPMID:22316170 PMID:32234424
Tspan9increases methylationISOTSPAN9 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of TSPAN9 3' UTRPMID:27901495
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