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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304695
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc39a13
Name: solute carrier family 39 member 13
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc39a13increases expressionEXP 6480464CTDZinc deficiency results in increased expression of SLC39A13 mRNAPMID:20859692
Slc39a13affects localizationISOSlc39a13 (Mus musculus)6480464CTDSLC39A13 protein affects the localization of ZincPMID:18985159
Slc39a13increases expressionISOSlc39a13 (Mus musculus)6480464CTDZinc results in increased expression of SLC39A13 mRNAPMID:22228435
Slc39a13increases transportISOSLC39A13 (Homo sapiens)6480464CTDSLC39A13 protein results in increased transport of ZincPMID:18326752
Slc39a13multiple interactionsISOSlc39a13 (Mus musculus)6480464CTD[[Zinc affects the localization of MTF1 protein] promotes the reaction [MTF1 protein binds to SLC39A13 promoter]] which results in increased expression of SLC39A13 mRNA; [Zinc affects the localization of MTF1 protein] promotes the reaction [MTF1 protein binds to SLC39A13 promoter]; [Zinc deficiency promotes the reaction [NFIC protein binds to SLC39A13 protein]] which results in decreased expression of SLC39A13 mRNA; Zinc deficiency promotes the reaction [NFIC protein binds to SLC39A13 protein]PMID:22228435
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