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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304658
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tenm4
Name: teneurin transmembrane protein 4
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tenm4affects expressionISOTenm4 (Mus musculus)6480464CTDBenzo(a)pyrene affects the expression of TENM4 mRNAPMID:22342234
Tenm4affects methylationISOTENM4 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of TENM4 5' UTR; Benzo(a)pyrene affects the methylation of TENM4 intronPMID:27901495 PMID:30157460
Tenm4decreases expressionISOTenm4 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of TENM4 mRNAPMID:20713471 PMID:22228805 PMID:22610609
Tenm4decreases methylationISOTenm4 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased methylation of TENM4 exon; Benzo(a)pyrene results in decreased methylation of TENM4 intronPMID:27901495
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