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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304553
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifi35
Name: interferon-induced protein 35
Acc ID: CHEBI:27470
Term: folic acid
Definition: An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
Chemical ID: MESH:D005492
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifi35increases expressionISOIfi35 (Mus musculus)6480464CTDFolic Acid deficiency results in increased expression of IFI35 mRNAPMID:32304770
Ifi35multiple interactionsISOIfi35 (Mus musculus)6480464CTDFolic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of IFI35 mRNA]PMID:22206623
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