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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303284
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Acc ID: CHEBI:78649
Term: edelfosine
Definition: A racemate comprising equimolar amounts of (R)- and (S)-edelfosine.
Chemical ID: MESH:C026659
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpa1multiple interactionsISOTRPA1 (Homo sapiens)6480464CTDedelfosine inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]; edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [cinnamaldehyde results in increased activity of TRPA1 protein]]PMID:17571167
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