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GENE - TERM ANNOTATION REPORT

RGD ID: 12260688
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: MYH10
Name: myosin heavy chain 10
Acc ID: GO:0016459
Term: myosin complex
Definition: A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.
Definition Source(s): GOC:mah, Wikipedia:Myosin
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MYH10part_ofIEAInterPro:IPR001609 or InterPro:IPR002928 or InterPro:IPR004009150520179InterPro GO_REF:0000002
MYH10part_ofIEAUniProtKB-KW:KW-0518150520179UniProt GO_REF:0000043
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