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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12224854
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: GSR
Name: glutathione-disulfide reductase
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSRdecreases activityEXP 6480464CTDsodium arsenite results in decreased activity of GSR proteinPMID:18163546
GSRmultiple interactionsEXP 6480464CTD[monoisoamyl-2,3-dimercaptosuccinate co-treated with Succimer] inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; monoisoamyl-2,3-dimercaptosuccinate inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]PMID:18163546
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