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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10217
Species: Mus musculus
RGD Object: Gene
Symbol: Atp7b
Name: ATPase, copper transporting, beta polypeptide
Acc ID: CHEBI:17750
Term: glycine betaine
Definition: The amino acid betaine derived from glycine.
Chemical ID: MESH:D001622
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp7bmultiple interactionsEXP 6480464CTDATP7B protein mutant form promotes the reaction [Betaine results in increased abundance of S-Adenosylmethionine]; Betaine inhibits the reaction [ATP7B protein mutant form results in increased abundance of Copper]; Betaine inhibits the reaction [ATP7B protein mutant form results in increased expression of TNF mRNA]PMID:22945834
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